Article
DNA sequence analysis of the gene encoding the HTLV-I p21e transmembrane protein reveals inter- and intraisolate genetic heterogeneity.
Virology - 1 Feb 1992
Ehrlich G D, Andrews J, Sherman M P, Greenberg S J, Poiesz B J
Abstract excerpt
DNA sequence analysis was performed on a 235-bp region of the p21 e transmembrane protein gene of the human T-cell lymphoma/leukemia virus type I (HTLV-I) which encompassess the putative immunosuppressive peptide. Polymerase chain reaction-based amplification was used to generate multiple molecular clones from isolates derived from fresh or cultured cells from 19 individuals. A dendrogram was constructed using...
Topics
- Base Sequence
- DNA, Viral
- Gene Products, env
- Genes, Viral
- Genetic Variation
- HTLV-I Infections
- Human T-lymphotropic virus 1
- Humans
- Molecular Sequence Data
- Retroviridae Proteins, Oncogenic
- Sequence Homology, Nucleic Acid
