Article
Initiation of vesicular stomatitis virus mutant polR1 transcription internally at the N gene in vitro.
Journal of virology - 1 Feb 1997
Chuang J L, Perrault J
Abstract excerpt
The vesicular stomatitis virus (VSV) polymerase is thought to initiate transcription of its genome by first copying a small leader RNA complementary to the 3' end of the template. The polR VSV mutants, in contrast to wild-type virus, frequently read through the leader termination site during transcription in vitro. To shed light on polymerase termination and reinitiation events at the crucial leader-N gene...
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