Article
Relative sensitivity of parkin and other cysteine-containing enzymes to stress-induced solubility alterations.
The Journal of biological chemistry - 20 Apr 2007
Wong Esther S P, Tan Jeanne M M, Wang Cheng, Zhang Zhenshui, Tay Shiam-Peng, Zaiden Norazean, Ko Han Seok, Dawson Valina L, Dawson Ted M, Lim Kah-Leong
Abstract excerpt
Loss of parkin function is a predominant cause of familial Parkinsonism. Emerging evidence also suggests that parkin expression variability may confer a risk for sporadic Parkinson disease. We have recently demonstrated that a wide variety of Parkinson disease-linked stressors, including dopamine...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.