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Article

Localization and expression of substance P in transgenic mice overexpressing human APP751 with the London (V717I) and Swedish (K670M/N671L) mutations.

Brain research - 27 Apr 2007

Willis Michael, Hutter-Paier Birgit, Wietzorrek Georg, Windisch Manfred, Humpel Christian, Knaus Hans Günther, Marksteiner Josef

Abstract excerpt

Substance P-like immunoreactivity (-LI) is found in neuritic plaques, and is reduced in patients suffering from Alzheimer disease (AD). In this study, we examined the distribution and expression of substance P in transgenic mice overexpressing human amyloid precursor protein (hAPP) APP751 with th...

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Identifiers

PMID: 17328871
DOI: 10.1016/j.brainres.2007.01.080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17328871-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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