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Article

Radiotherapy diagnostic biomarkers in radioresistant human H460 lung cancer stem-like cells

1 Feb 2016

Abstract excerpt

Tumor cell radioresistance is a major contributor to radiotherapy failure, highlighting the importance of identifying predictive biomarkers for radioresistance. In this work, we established a radioresistant H460 (RR-H460) cell line from parental radiosensitive H460 lung cancer cells by exposure to fractionated radiation. The radiation-resistant, anti-apoptotic phenotype of RR-H460 cell lines was confirmed by...

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PMID: 26901847
DOI: 10.1080/15384047.2016.1139232

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