Article
RSR1, a ras-like gene homologous to Krev-1 (smg21A/rap1A): role in the development of cell polarity and interactions with the Ras pathway in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Feb 1992
Ruggieri R, Bender A, Matsui Y, Powers S, Takai Y, Pringle J R, Matsumoto K
Abstract excerpt
The Saccharomyces cerevisiae ras-like gene RSR1 is particularly closely related to the mammalian gene Krev-1 (also known as smg21A and rap1A). RSR1 was originally isolated as a multicopy suppressor of a cdc24 mutation, which causes an inability to bud or establish cell polarity. Deletion of RSR1 itself does not affect growth but causes a randomization of bud position. We have now constructed mutant alleles of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.