Article
RSR1, a ras-like gene homologous to Krev-1 (smg21A/rap1A): role in the development of cell polarity and interactions with the Ras pathway in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Feb 1992
Ruggieri R, Bender A, Matsui Y, Powers S, Takai Y, Pringle J R, Matsumoto K
Abstract excerpt
The Saccharomyces cerevisiae ras-like gene RSR1 is particularly closely related to the mammalian gene Krev-1 (also known as smg21A and rap1A). RSR1 was originally isolated as a multicopy suppressor of a cdc24 mutation, which causes an inability to bud or establish cell polarity. Deletion of RSR1...
Topics
- Adenylyl Cyclases
- Cell Polarity
- GTP-Binding Proteins
- Genes, Fungal
- Genes, ras
- Microscopy, Fluorescence
- Mutation
- Plasmids
- Proto-Oncogene Proteins p21(ras)
- Saccharomyces cerevisiae
- Suppression, Genetic
- Temperature
- rap GTP-Binding Proteins