Article
Prevalence of X4 tropic viruses in patients recently infected with HIV-1 and lack of association with transmission of drug resistance.
The Journal of antimicrobial chemotherapy - 1 Apr 2007
de Mendoza Carmen, Rodriguez Carmen, García Federico, Eiros José M, Ruíz Lidia, Caballero Estrella, Aguilera Antonio, Leiva Pilar, Colomina Javier, Gutierrez Felix, del Romero Jorge, Aguero Jesús, Soriano Vincent
Abstract excerpt
BACKGROUND: HIV-1 co-receptor usage may play a critical role in AIDS pathogenesis. Information on viral tropism in HIV-1 seroconverters is scarce, as is the relationship with transmission of drug-resistant viruses. METHODS: All consecutive HIV-1 seroconverters seen between January 1997 and December 2005 in 17 Spanish hospitals were retrospectively analysed. V3 loop amino acid sequences derived from plasma RNA at...
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