Resolving the latent structure of schizophrenia endophenotypes using expectation-maximization-based finite mixture modeling.

Abstract excerpt

Prior research has focused on the latent structure of endophenotypic markers of schizophrenia liability, or schizotypy. The work supports the existence of 2 relatively distinct latent classes and derives largely from the taxometric analysis of psychometric values. The present study used finite mixture modeling as a technique for discerning latent structure and the laboratory-measured endophenotypes of sustained...

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