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Article

Interethnic difference in thiopurine methyltransferase activity.

Clinical pharmacology and therapeutics - 1 Jan 1992

Klemetsdal B, Tollefsen E, Loennechen T, Johnsen K, Utsi E, Gisholt K, Wist E, Aarbakke J

Abstract excerpt

A number of metabolic pathways are subject to both genetic polymorphism and interethnic differences. A catabolic pathway of 6-mercaptopurine, red blood cell (RBC) thiopurine methyltransferase (TPMT) activity showed genetic polymorphism in Caucasians, but variation according to ethnicity has not been studied. We investigated if red blood cell thiopurine methyltransferase was subject to interethnic variation in a...

Topics

Adolescent
Adult
Aged
Animals
Cats
Erythrocytes
Ethnicity
Female
Genetic Variation
Humans
Male
Methyltransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Norway

White People

Source

Identifiers

PMID: 1732075
DOI: 10.1038/clpt.1992.4

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1732075-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Interethnic difference in thiopurine methyltransferase activity.PMID 1732075Read ↗

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