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Article

Epidermal growth factor receptor mutations in lung cancer.

Nature reviews. Cancer - 1 Mar 2007

Sharma Sreenath V, Bell Daphne W, Settleman Jeffrey, Haber Daniel A

Abstract excerpt

The development and clinical application of inhibitors that target the epidermal growth factor receptor (EGFR) provide important insights for new lung cancer therapies, as well as for the broader field of targeted cancer therapies. We review the results of genetic, biochemical and clinical studies focused on somatic mutations of EGFR that are associated with the phenomenon of oncogene addiction, describing...

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Share to Antineoplastic Agents
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17318210
DOI: 10.1038/nrc2088

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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