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Article

Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers?

Trends in molecular medicine - 1 Oct 2004

Gazdar Adi F, Shigematsu Hisayuki, Herz Joachim, Minna John D

Abstract excerpt

The epidermal growth factor receptor (EGFR) gene product is a receptor tyrosine kinase (TK) that affects many important downstream pathways. The recent finding that mutations in EGFR predict the response of lung cancers to therapies that target the TK domain of the gene product has generated cons...

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Source

Identifiers

PMID: 15464447
DOI: 10.1016/j.molmed.2004.08.008

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15464447-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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