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Article

Execution of the circadian negative feedback loop in Neurospora requires the ATP-dependent chromatin-remodeling enzyme CLOCKSWITCH.

Molecular cell - 23 Feb 2007

Belden William J, Loros Jennifer J, Dunlap Jay C

Abstract excerpt

In the Neurospora circadian system, the transcription factors White Collar-1 (WC-1) and White Collar-2 (WC-2) activate expression of frq, whose gene product inhibits its own expression. The WC proteins are thought to form an obligate complex; however, chromatin immunoprecipitation (ChIP) indicates that WC-2 binds to the frq promoter in a rhythmic fashion, whereas WC-1 is bound continuously. Small oscillations in...

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Source

Identifiers

PMID: 17317630
DOI: 10.1016/j.molcel.2007.01.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Execution of the circadian negative feedback loop in Neurospora requires the ATP-dependent chromatin-remodeling enzyme CLOCKSWITCH.PMID 17317630Read ↗

Neurospora WC-1 recruits SWI/SNF to remodel frequency and initiate a circadian cycle.Semantic proximity Read ↗

FRQ-interacting RNA helicase mediates negative and positive feedback in the Neurospora circadian clock.Semantic proximity Read ↗

Domains required for the interaction of the central negative element FRQ with its transcriptional activator WCC within the core circadian clock of Neurospora.Semantic proximity Read ↗

Light-independent phosphorylation of WHITE COLLAR-1 regulates its function in the Neurospora circadian negative feedback loop.Semantic proximity Read ↗

PAS domain-mediated WC-1/WC-2 interaction is essential for maintaining the steady-state level of WC-1 and the function of both proteins in circadian clock and light responses of Neurospora.Semantic proximity Read ↗

Interconnected feedback loops in the Neurospora circadian system.Semantic proximity Read ↗

Transcriptional repression of frequency by the IEC-1-INO80 complex is required for normal Neurospora circadian clock function.Semantic proximity Read ↗

Roles for WHITE COLLAR-1 in circadian and general photoperception in Neurospora crassa.Semantic proximity Read ↗

The genetics of circadian rhythms in Neurospora.Semantic proximity Read ↗

Temperature-sensitive and circadian oscillators of Neurospora crassa share components.Semantic proximity Read ↗

CKI and CKII mediate the FREQUENCY-dependent phosphorylation of the WHITE COLLAR complex to close the Neurospora circadian negative feedback loop.Semantic proximity Read ↗

Circadian regulation of the light input pathway in Neurospora crassa.Semantic proximity Read ↗

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