Article
Impact of T-cell receptor Vbeta haplotypes on the development of dermatitis in DS-Nh mice: synergistic production of interleukin-13 caused by staphylococcal enterotoxin C and peptide glycans from Staphylococcus aureus.
Immunology - 1 May 2007
Yoshioka Takeshi, Imura Kinichi, Hikita Ichiro, Hirasawa Tsutomu, Sakata Tsuneaki, Matsutani Takaji, Horikawa Tatsuya, Arimura Akinori
Abstract excerpt
Although the pathogenic role of interleukin-13 (IL-13) is a key for atopic dermatitis (AD), the mechanism of IL-13 production in AD remains unclear. To investigate the role of the T-cell receptor Vbeta (TCR Vbeta) haplotype in the development of dermatitis and the production of IL-13 in the natur...
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