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Article

Linkage of atherogenic lipoprotein phenotype to the low density lipoprotein receptor locus on the short arm of chromosome 19.

Proceedings of the National Academy of Sciences of the United States of America - 15 Jan 1992

Nishina P M, Johnson J P, Naggert J K, Krauss R M

Abstract excerpt

The atherogenic lipoprotein phenotype (ALP) is a common heritable trait characterized by a predominance of small, dense low density lipoprotein (LDL) particles (subclass pattern B), increased levels of triglyceride-rich lipoproteins, reductions in high density lipoprotein, and a 3-fold increased risk of myocardial infarction. Significant two-point linkage was found between ALP and the LDL receptor locus on the...

Topics

Arteriosclerosis
Chromosome Mapping
Chromosomes, Human, Pair 19
Genetic Linkage
Genetic Markers
Humans
Lipoproteins, HDL
Lipoproteins, LDL
Pedigree
Phenotype
Receptor, Insulin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, LDL

Source

Open in PubMed Open full text

Identifiers

PMID: 1731344
DOI: 10.1073/pnas.89.2.708
PMCID: PMC48308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1731344-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Linkage of atherogenic lipoprotein phenotype to the low density lipoprotein receptor locus on the short arm of chromosome 19.PMID 1731344Read ↗

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