Article
Linkage of high-density lipoprotein-cholesterol concentrations to a locus on chromosome 9p in Mexican Americans.
Nature genetics - 1 Jan 2002
Arya Rector, Duggirala Ravindranath, Almasy Laura, Rainwater David L, Mahaney Michael C, Cole Shelley, Dyer Thomas D, Williams Ken, Leach Robin J, Hixson James E, MacCluer Jean W, O'Connell Peter, Stern Michael P, Blangero John
Abstract excerpt
High-density lipoproteins (HDLs) are anti-atherogenic lipoproteins that have a major role in transporting cholesterol from peripheral tissues to the liver, where it is removed. Epidemiologic studies have shown that low levels of high-density lipoprotein-cholesterol (HDL-C) are associated with an increased incidence of coronary heart disease and an increased mortality rate, indicating a protective role of high...
Topics
- Adult
- Aged
- Cardiovascular Diseases
- Case-Control Studies
- Cholesterol, HDL
- Chromosome Mapping
- Chromosomes, Human, Pair 9
- Comorbidity
- Diabetes Mellitus, Type 2
- Female