Article
Evidence for linkage and association to alcohol dependence on chromosome 19.
Genetic epidemiology - 1 Jan 1999
Valdes A M, McWeeney S K, Thomson G
Abstract excerpt
An association study on markers showing suggestive evidence for linkage to severe alcoholism was performed on the Collaborative Study on the Genetics of Alcoholism (COGA) data set. Our linkage study was restricted to the autosomal markers on chromosomes 2, 3, 4, 13, and 19, with low homozygosity (below 30%) and high identity-by-state sharing in affected sib pairs (ASPs). We used a strict phenotype definition,...
Topics
- Alcoholism
- Alleles
- Chromosomes, Human, Pair 19
- Genetic Linkage
- Genetic Markers
- Genetic Testing
- Haplotypes
- Humans
- Personality
- Phenotype