Article
The effect of methotrexate on the expression of cell adhesion molecules and activation molecule CD69 in psoriasis.
Journal of the European Academy of Dermatology and Venereology : JEADV - 1 Mar 2007
Torres-Alvarez B, Castanedo-Cazares J P, Fuentes-Ahumada C, Moncada B
Abstract excerpt
BACKGROUND: The mechanism of the action of methotrexate (MTX) in the treatment of psoriasis has not been completely elucidated. OBJECTIVE: To assess the effect of MTX on the expression of intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), E-selectin, activation molecule CD69 and T-cell phenotype in skin specimens from patients with psoriasis. METHODS: We performed an...
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