Article
Changes in T-cell phenotype and adhesion molecules expression in psoriatic lesions after low-dose cyclosporin therapy.
Journal of cutaneous pathology - 1 Oct 1996
Servitje O, Bordas X, Serón D, Vidaller A, Moreno A, Curcó N, Sais G, Peyrí J
Abstract excerpt
Cyclosporin is a very effective treatment for severe psoriasis, but its exact mechanism of action in this disease is not completely understood. It has been hypothesized that the drug could act through the inhibition of the expression of certain cell adhesion molecules on the keratinocytes prior t...
Topics
- Adult
- Cell Adhesion Molecules
- Cyclosporine
- Dose-Response Relationship, Drug
- Female
- Humans
- Immunohistochemistry
- Lymphocyte Count
- Male
- Middle Aged
- Phenotype
- Psoriasis
- T-Lymphocytes
