Carboxy terminally truncated forms of ribophorin I are degraded in pre-Golgi compartments by a calcium-dependent process.

doi:10.1083/jcb.116.1.57

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Article

Carboxy terminally truncated forms of ribophorin I are degraded in pre-Golgi compartments by a calcium-dependent process.

The Journal of cell biology - 1 Jan 1992

Tsao Y S, Ivessa N E, Adesnik M, Sabatini D D, Kreibich G

Abstract excerpt

Two COOH terminally truncated variants of ribophorin I (RI), a type I transmembrane glycoprotein of 583 amino acids that is segregated to the rough portions of the ER and is associated with the protein-translocating apparatus of this organelle, were expressed in permanent HeLa cell transformants. Both variants, one membrane anchored but lacking part of the cytoplasmic domain (RL467) and the other consisting of...

Topics

Animals
Base Sequence
Calcium
Carbonyl Cyanide m-Chlorophenyl Hydrazone
Endoplasmic Reticulum
Genetic Variation
Golgi Apparatus
HeLa Cells
Humans
Kinetics
Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Monensin

Oligodeoxyribonucleotides

Phenanthrolines

Plasmids

Rats

Restriction Mapping

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Identifiers

PMID: 1730749
DOI: 10.1083/jcb.116.1.57
PMCID: PMC2289265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1730749-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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