An enzymatic mutant of Shiga-like toxin II variant is a vaccine candidate for edema disease of swine.

doi:10.1128/iai.60.2.485-490.1992

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Article

An enzymatic mutant of Shiga-like toxin II variant is a vaccine candidate for edema disease of swine.

Infection and immunity - 1 Feb 1992

Gordon V M, Whipp S C, Moon H W, O'Brien A D, Samuel J E

Abstract excerpt

Edema disease (ED) of weanling pigs is caused by an infection with Escherichia coli that produces Shiga-like toxin II variant (SLT-IIv). Pathology identical to that caused by ED can be duplicated in pigs that are injected with less than 10 ng of purified SLT-IIv per kg of body weight. Therefore,...

Topics

Animals
Animals, Newborn
Bacterial Toxins
Bacterial Vaccines
Edema Disease of Swine
Enterotoxins
Mutation
Shiga Toxin 2
Structure-Activity Relationship
Swine
Toxoids

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