Article
Association and linkage analysis of COL1A1 and AHSG gene polymorphisms with femoral neck bone geometric parameters in both Caucasian and Chinese nuclear families.
Acta pharmacologica Sinica - 1 Mar 2007
Jiang Hui, Lei Shu-Feng, Xiao Su-Mei, Chen Yuan, Sun Xiao, Yang Fang, Li Li-Ming, Wu Shan, Deng Hong-Wen
Abstract excerpt
AIM: To simultaneously investigate the contribution of the alpha 1 chain of collagen type 1 (COL1A1) and alpha2-HS-glycoprotein (AHSG) genes to the variation of bone geometric parameters in both Caucasians and Chinese. METHODS: Six hundred and five Caucasian individuals from 157 nuclear families and 1228 Chinese subjects from 400 nuclear families were genotyped at the AHSG-SacI, COL1A1- PCOL2 and Sp1...
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