Article
Plasmodium berghei: in vivo generation and selection of karyotype mutants and non-gametocyte producer mutants.
Experimental parasitology - 1 Feb 1992
Janse C J, Ramesar J, van den Berg F M, Mons B
Abstract excerpt
We previously reported that karyotype and gametocyte-producer mutants spontaneously arose during in vivo asexual multiplication of Plasmodium berghei. Here we studied the rate of selection of these mutants in vivo. Gametocyte production and karyotype pattern were established at regular intervals during prolonged periods of asexual multiplication of clone 8417 of P. berghei. We found that karyotype mutants and...
Topics
- Animals
- Gametogenesis
- Genetic Variation
- Karyotyping
- Malaria
- Mice
- Mitosis
- Mutation
- Plasmodium berghei
- Reproduction, Asexual