Article
The effect of HIV-1 resistance mutations after first-line virological failure on the possibility to sequence antiretroviral drugs in second-line regimens.
Antiviral therapy - 1 Jan 2006
Maggiolo Franco, Ripamonti Diego, Torti Carlo, Arici Claudio, Antinori Andrea, Quiros-Roldan Eugenia, Minoli Lorenzo, Sighinolfi Laura, Nasta Paola, Suter Fredy
Abstract excerpt
BACKGROUND: One of the more vigorous debates in the field of highly active antiretroviral therapy (HAART) is how to start it and what the optimal drug sequence is. METHODS: A retrospective cohort analysis was performed. The aim was to evaluate which variables could influence the virological response to second-line genotypic-based HAART in patients with virological documented first-line HAART failure. A positive...
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