Article
[Resistance to antiretroviral agents: mechanism and study methods].
Presse medicale (Paris, France : 1983) - 1 Dec 1998
Bossi P, Calvez V, Bricaire F
Abstract excerpt
FREQUENT MUTATIONS: Associated with the high turnover rate of the HIV, frequent inverse transcriptase errors lead to a wide range of possible mutations. Certain mutations can modify the response to antiretroviral agents. The development of resistant strains is mediated by the selection pressure of antiretroviral agents and occurs at a very variable rate depending on the antiretroviral agent used. TO LOWER THE...
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