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Article

Widespread Decreased Expression of Immune Function Genes in Human Peripheral Blood Following Radiation Exposure

29 Oct 2013

Abstract excerpt

We report a large-scale reduced expression of genes in pathways related to cell-type specific immunity functions that emerges from microarray analysis 48 h after ex vivo γ-ray irradiation (0, 0.5, 2, 5, 8 Gy) of human peripheral blood from five donors. This response is similar to that seen in patients at 24 h after the start of total-body irradiation and strengthens the rationale for the ex vivo model as an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24168352
DOI: 10.1667/rr13343.1

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