Natural killer (NK) cell activity in mice with acute graft-versus-host reactions: characterization of a Thy-1+ NK-like cell with a broadened spectrum of lytic activity in the spleen and lymph nodes.

doi:10.1111/j.1365-3083.1991.tb02526.x

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Article

Natural killer (NK) cell activity in mice with acute graft-versus-host reactions: characterization of a Thy-1+ NK-like cell with a broadened spectrum of lytic activity in the spleen and lymph nodes.

Scandinavian journal of immunology - 1 May 1991

MacDonald G C, Gartner J G

Abstract excerpt

We have shown that acute (GVH) reactions produced in the parental-F1 hybrid combination, A/J----(C57BL/6 x A/J)F1 result in the activation of two cytotoxic cell populations: a host-derived Thy-1+/- natural killer (NK) cell with a lytic spectrum confined to YAC-1 targets, and a donor-derived Thy-1...

Topics

Animals
Antigens, Surface
Cell Separation
Cytotoxicity, Immunologic
Female
G(M1) Ganglioside
Glycosphingolipids
Graft vs Host Reaction
Interferons
Interleukin-2
Killer Cells, Natural

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymph Nodes

Mice

Mice, Inbred Strains

Phenotype

Spleen

Thy-1 Antigens

Source

Open in PubMed

Identifiers

PMID: 1709518
DOI: 10.1111/j.1365-3083.1991.tb02526.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1709518-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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