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Article

Influence of CYP2C9 and CYP2C19 genetic polymorphisms on pharmacokinetics of gliclazide MR in Chinese subjects.

British journal of clinical pharmacology - 1 Jul 2007

Zhang Yifan, Si Dayong, Chen Xiaoyan, Lin Nan, Guo Yingjie, Zhou Hui, Zhong Dafang

Abstract excerpt

AIMS: To investigate the influence of CYP2C9 and CYP2C19 genetic polymorphisms on the pharmacokinetics of gliclazide modified release (MR) in healthy Chinese subjects. METHODS: In a single-dose pharmacokinetic study, 24 healthy male subjects with various CYP2C9 and CYP2C19 genotypes received an oral dose of 30 mg gliclazide MR and plasma was sampled for 72 h postdose. In a multiple-dose pharmacokinetic study, 17...

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Identifiers

PMID: 17298483
DOI: 10.1111/j.1365-2125.2007.02846.x
PMCID: PMC2000619

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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