Article
Regulation of human LZIP expression by NF-kappaB and its involvement in monocyte cell migration induced by Lkn-1.
The Journal of biological chemistry - 13 Apr 2007
Jang Sung-Wuk, Kim Yoon Suk, Kim Yoon Rim, Sung Ho Joong, Ko Jesang
Abstract excerpt
Human LZIP is a transcription factor that is involved in leukocyte cell mobility. Expression of LZIP is known to differentially regulate monocyte cell migration induced by CCR1-dependent chemokines. However, its transcriptional regulation has not been characterized. Our results indicate that Lkn-1 induces LZIP expression in a time- and dose-dependent manner, and the induction of LZIP shows an immediate early...
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