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Article

GABRA6 genetic polymorphism is associated with the risk of functional heartburn in Chinese.

Journal of gastroenterology and hepatology - 1 Feb 2007

Lee Yi-Chia, Wang Hsiu-Po, Chiu Han-Mo, Huang Shih-Pei, Liao Shih-Cheng, Chen Ming-Fong, Lin Jaw-Town, Wu Ming-Shiang

Abstract excerpt

BACKGROUND AND AIM: Polymorphisms of GABA(A)alpha6 (GABRA6)-1521 and IL-1beta-511 have been linked with susceptibility to stress and gastric acid secretion. The aim of this study was to assess psychiatric profiles and GABRA6 and IL-1beta genotypes in functional heartburn, an important esophageal reflux condition. METHODS: Psychological symptoms were assessed with a Brief Symptom Rating Scale and personality...

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Source

Identifiers

PMID: 17295876
DOI: 10.1111/j.1440-1746.2006.04441.x

Genes

GABRA6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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