Article
Cholecystokinin- and cholecystokinin-B-receptor gene polymorphisms in panic disorder.
Journal of neural transmission. Supplementum - 1 Jan 2004
Hösing V G, Schirmacher A, Kuhlenbäumer G, Freitag C, Sand P, Schlesiger C, Jacob C, Fritze J, Franke P, Rietschel M, Garritsen H, Nöthen M M, Fimmers R, Stögbauer F, Deckert J
Abstract excerpt
Panic disorder like other neuropsychiatric disorders is believed to be caused by multiple psychosocial and biological factors. Several lines of evidence point to a role for the peptide neurotransmitter cholecystokinin in the pathogenesis of panic disorder. We therefore determined the allele and genotype frequencies of a single nucleotide polymorphism in the CCK gene (-36C>T) and one CT repeat polymorphism in the...
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