Article
A new stress sensor and risk factor for suicide: the T allele of the functional genetic variant in the GABRA6 gene.
Scientific reports - 10 Oct 2017
Gonda Xenia, Sarginson Jane, Eszlari Nora, Petschner Peter, Toth Zoltan G, Baksa Daniel, Hullam Gabor, Anderson Ian M, Deakin J F William, Juhasz Gabriella, Bagdy Gyorgy
Abstract excerpt
Low GABA transmission has been reported in suicide, and GABRA6 rs3219151 T allele has been associated with greater physiological and endocrine stress response in previous studies. Although environmental stress also plays a role in suicide, the possible role of this allele has not been investigated in this respect. In our present study effect of rs3219151 of GABRA6 gene in interaction with recent negative life...
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