Article
Association of SNPs rs6498169 and rs10984447 with multiple sclerosis in Saudi patients: a model of the usefulness of familial aggregates in identifying genetic linkage in a multifactorial disease.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Oct 2012
Al Jumah M, Al Balwi M, Hussein M, Kojan S, Al Khathaami A, Al Fawaz M, Al Muzaini B, Jawhary A, Al Abdulkareem I
Abstract excerpt
OBJECTIVE: Genome-Wide association studies (GWAS) showed an association between subset of single-nucleotide polymorphism (SNPs) and multiple sclerosis. Our study aims to study this association in Saudi familial multiple sclerosis patients. METHODS: Four subject groups were used in this study: sporadic MS (MS patients without family history), FMS (MS patients who have at least one family member diagnosed with MS),...
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