Interaction between Streptococcus pneumoniae and Staphylococcus aureus Generates·OH Radicals That Rapidly Kill Staphylococcus aureus Strains

Abstract excerpt

Streptococcus pneumoniae strains produce hydrogen peroxide (H2O2) to kill bacteria in the upper airways, including pathogenic Staphylococcus aureus strains. The targets of S. pneumoniae -produced H2O2have not been discovered, in part because of a lack of knowledge about the underlying molecular mechanism. We demonstrated that an increased density of S. pneumoniae kills S. aureus by means of H2O2produced by two...

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