Article
Overexpression of MexAB-OprM efflux pump in carbapenem-resistant Pseudomonas aeruginosa.
Archives of microbiology - 1 Aug 2016
Pan Ya-Ping, Xu Yuan-Hong, Wang Zhong-Xin, Fang Ya-Ping, Shen Ji-Lu
Abstract excerpt
Efflux pump systems are one of the most important mechanisms conferring multidrug resistance in Pseudomonas aeruginosa. MexAB-OprM efflux pump is one of the largest multi-drug resistant efflux pumps with high-level expression, which is controlled by regulatory genes mexR, nalC, and nalD. This study investigated the role of efflux pump MexAB-OprM in 75 strains of carbapenem-resistant P. aeruginosa and evaluated...
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