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Cell biological analysis reveals an essential role for Pfcerli2 in erythrocyte invasion by malaria parasites

9 Feb 2022

Abstract excerpt

Merozoite invasion of host red blood cells (RBCs) is essential for survival of the human malaria parasite Plasmodium falciparum. Proteins involved with RBC binding and invasion are secreted from dual-club shaped organelles at the apical tip of the merozoite called the rhoptries. Here we characterise P. falciparum Cytosolically Exposed Rhoptry Leaflet Interacting protein 2 (PfCERLI2), as a rhoptry bulb protein...

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PMID: 35140336
DOI: 10.1038/s42003-022-03020-9

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Cell biological analysis reveals an essential role for Pfcerli2 in erythrocyte invasion by malaria parasitesPMID 35140336Read ↗

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