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Article

Early life stress alters adult serotonin 2C receptor pre-mRNA editing and expression of the alpha subunit of the heterotrimeric G-protein G q.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 7 Feb 2007

Bhansali Punita, Dunning Jane, Singer Sarah E, David Leora, Schmauss Claudia

Abstract excerpt

Infant maternal separation, a paradigm of early life stress in rodents, elicits long-lasting changes in gene expression that persist into adulthood. In BALB/c mice, an inbred strain with spontaneously elevated anxiety and stress reactivity, infant maternal separation led to increased depression-like behavioral responses to adult stress and robustly increased editing of serotonin 2C receptor pre-mRNA. Chronic...

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Source

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Identifiers

PMID: 17287521
DOI: 10.1523/JNEUROSCI.4632-06.2007
PMCID: PMC6673584

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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