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Article

Trans-generational effects of early life stress: the role of maternal behavior.

Scientific reports - 2 May 2014

Schmauss Claudia, Lee-McDermott Zoe, Medina Liorimar Ramos

Abstract excerpt

Using a rodent paradigm of early life stress, infant maternal separation (IMS), we examined whether IMS-triggered behavioral and epigenetic phenotypes of the stress-susceptible mouse strain Balb/c are propagated across generations. These phenotypes include impaired emotional behavior and deficits in executive cognitive functions in adulthood, and they are associated with increased acetylation of histone H4K12...

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Identifiers

PMID: 24786242
DOI: 10.1038/srep04873
PMCID: PMC4007084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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