Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Primary pigmented nodular adrenocortical disease reveals insulin-like growth factor binding protein-2 regulation by protein kinase A.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 1 Apr 2007

Shi Zonggao, Henwood Maria J, Bannerman Peter, Batista Dalia, Horvath Anelia, Guttenberg Marta, Stratakis Constantine A, Grimberg Adda

Abstract excerpt

OBJECTIVE: Primary pigmented nodular adrenocortical disease (PPNAD) can occur as an isolated trait or part of Carney complex, a familial lentiginosis-multiple endocrine neoplasia syndrome frequently caused by mutations in PRKAR1A, which encodes the 1alpha regulatory subunit of protein kinase A (P...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Cortex Neoplasms
Share to Cell Proliferation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclic AMP-Dependent Protein Kinase RIalpha Subunit

Share to Cyclic AMP-Dependent Protein Kinases

Share to Insulin-Like Growth Factor II

Share to Multiple Endocrine Neoplasia

Share to Protein Kinase Inhibitors

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 17280861
DOI: 10.1016/j.ghir.2006.12.004
PMCID: PMC2577759

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17280861-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Primary pigmented nodular adrenocortical disease reveals insulin-like growth factor binding protein-2 regulation by protein kinase A.PMID 17280861Read ↗

PRKAR1A Mutations and protein kinase A interactions with other signaling pathways in the adrenal cortex.Semantic proximity Read ↗

Insulin-like growth factor 2 (IGF2) expression in adrenocortical disease due to PRKAR1A mutations compared to other benign adrenal tumors.Semantic proximity Read ↗

mTOR pathway is activated by PKA in adrenocortical cells and participates in vivo to apoptosis resistance in primary pigmented nodular adrenocortical disease (PPNAD)Semantic proximity Read ↗

Protein kinase A and its role in human neoplasia: the Carney complex paradigm.Semantic proximity Read ↗

Down-Regulation of Regulatory Subunit Type 1A of Protein Kinase A Leads to Endocrine and Other TumorsSemantic proximity Read ↗

A novel PRKAR1A mutation associated with primary pigmented nodular adrenocortical disease and the Carney complex.Semantic proximity Read ↗

Protein kinase A alterations in endocrine tumors.Semantic proximity Read ↗

Molecular analysis of the cyclic AMP-dependent protein kinase A (PKA) regulatory subunit 1A (PRKAR1A) gene in patients with Carney complex and primary pigmented nodular adrenocortical disease (PPNAD) reveals novel mutations and clues for pathophysiology: augmented PKA signaling is associated with adrenal tumorigenesis in PPNAD.Semantic proximity Read ↗

Human tumors associated with Carney complex and germline PRKAR1A mutations: a protein kinase A disease!Semantic proximity Read ↗

PRKACA: the catalytic subunit of protein kinase A and adrenocortical tumorsSemantic proximity Read ↗

MicroRNA Signature of Primary Pigmented Nodular Adrenocortical Disease: Clinical Correlations and Regulation of <i>Wnt</i> SignalingSemantic proximity Read ↗

Protein Kinase A Alterations in Adrenocortical TumorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.