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Article

Protein kinase A and its role in human neoplasia: the Carney complex paradigm.

1 Jun 2004

Abstract excerpt

The type 1 alpha regulatory subunit (R1alpha) of cAMP-dependent protein kinase A (PKA) (PRKAR1A) is an important regulator of the serine-threonine kinase activity catalyzed by the PKA holoenzyme. Carney complex (CNC) describes the association 'of spotty skin pigmentation, myxomas, and endocrine overactivity'; CNC is in essence the latest form of multiple endocrine neoplasia to be described and affects the...

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PMID: 15163302
DOI: 10.1677/erc.0.0110265

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Source receipt: pubmed, retrieved 7 Sept 2026.

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