Article
Identification of early disease progression in an ALS rat model.
Neuroscience letters - 30 Mar 2007
Thonhoff Jason R, Jordan Paivi M, Karam Joseph R, Bassett Brandon L, Wu Ping
Abstract excerpt
Transgenic rat models of amyotrophic lateral sclerosis (ALS) have recently been developed. Most assays of ALS-symptoms in these models monitor disease onset accurately, but do not identify individuals that will develop these symptoms before the motor deficits become apparent. Peak bodyweight has recently been shown to indicate affected individuals before motor deficits become apparent. However, it must be...
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