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Article

Data mining in a behavioral test detects early symptoms in a model of amyotrophic lateral sclerosis.

Behavioral neuroscience - 1 Aug 2008

Kafkafi Neri, Yekutieli Daniel, Yarowsky Paul, Elmer Gregory I

Abstract excerpt

"What's wrong with my genetically engineered animal?" is a common yet often difficult to answer question in behavioral phenotyping. We present here a method termed Pattern Array for mining movement patterns and isolating those that best capture an effect of a genetic manipulation. We demonstrate the method by searching for early motor symptoms in the open-field behavior of SOD1 mutant rats, an animal model of...

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Source

Identifiers

PMID: 18729631
DOI: 10.1037/0735-7044.122.4.777

Genes

SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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