Article
Induction of human umbilical cord blood-derived stem cells with embryonic stem cell phenotypes into insulin producing islet-like structure.
Biochemical and biophysical research communications - 23 Mar 2007
Sun Bo, Roh Kyung-Hwan, Lee Sae-Rom, Lee Yong-Soon, Kang Kyung-Sun
Abstract excerpt
Success in islet-transplantation-based therapies for type I diabetes, coupled with a worldwide shortage of transplant-ready islets, has motivated efforts to develop renewable sources of islet-replacement tissue. Embryonic stem cells (ESCs) have been successfully induced into insulin producing islet-like structure in several studies. However, the source of the ESCs has presented ethical and technical concerns....
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