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Directed engineering of umbilical cord blood stem cells to produce C‐peptide and insulin

22 May 2007

Abstract excerpt

OBJECTIVES: In this study, we investigated the potential of umbilical cord blood stem cell lineages to produce C-peptide and insulin. MATERIALS AND METHODS: Lineage negative, CD133+ and CD34+ cells were analyzed by flow cytometry to assess expression of cell division antigens. These lineages were expanded in culture and subjected to an established protocol to differentiate mouse embryonic stem cells (ESCs) toward...

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PMID: 17531081
DOI: 10.1111/j.1365-2184.2007.00439.x

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