Article
PAX9 and TGFB3 are linked to susceptibility to nonsyndromic cleft lip with or without cleft palate in the Japanese: population-based and family-based candidate gene analyses.
Journal of human genetics - 1 Jan 2006
Ichikawa Eisaburo, Watanabe Akira, Nakano Yoko, Akita Sadanori, Hirano Akiyoshi, Kinoshita Akira, Kondo Shinji, Kishino Tatsuya, Uchiyama Takeshi, Niikawa Norio, Yoshiura Koh-Ichiro
Abstract excerpt
The prevalence of nonsyndromic cleft lip with or without cleft palate (CL/P) and cleft palate only (CPO) are believed to be higher in the Japanese than in Americans, Europeans or Africans. The purpose of this study was to investigate, in a Japanese population, relationships between CL/P or CPO and seven candidate genes (TGFB3, DLX3, PAX9, CLPTM1, TBX10, PVRL1, TBX22) that showed positive associations in other...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.