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Article

Association of KLOTHO gene polymorphisms with knee osteoarthritis in Greek population.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Nov 2008

Tsezou Aspasia, Furuichi Tatsuya, Satra Maria, Makrythanasis Periklis, Ikegawa Shiro, Malizos Konstantinos N

Abstract excerpt

Based on the fact that klotho-deficient mice exhibit multiple aging phenotypes, including osteopenia and subchondral sclerosis of joints and on the recent observation that KLOTHO gene plays an important role in calcium/phosphate homeostasis, we explored the possibility whether human KLOTHO gene polymorphisms are associated with osteoarthritis (OA). A total of 752 individuals participated in the study. The knee OA...

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Identifiers

PMID: 18465812
DOI: 10.1002/jor.20634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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