Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Screen p53 mutations in hepatocellular carcinoma by FASAY: a novel splicing mutation.

Journal of Zhejiang University. Science. B - 1 Feb 2007

Wu Xiao-mo, Fu Jing-geng, Ge Wang-zhong, Zhu Jiang-yan, Wang Jun-yong, Zhang Wei, Qian Wei, Huo Ke-ke

Abstract excerpt

OBJECTIVE: To establish a routine procedure for the detection of p53 mutations in hepatocellular carcinoma (HCC) surgical resections using the FASAY (functional analysis of separated alleles of p53 on yeast) procedure. METHODS: p53 status was analyzed by FASAY and cDNA sequencing in 50 cases of HCC. After the extraction of RNA from the frozen tumor and corresponding normal tissues, reverse transcription RT-PCR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Testing
Share to Alternative Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Hepatocellular

Share to DNA Mutational Analysis

Share to Liver Neoplasms

Share to Reproducibility of Results

Share to Sensitivity and Specificity

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 17266182
DOI: 10.1631/jzus.2007.B0081
PMCID: PMC1791066

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Screen p53 mutations in hepatocellular carcinoma by FASAY: a novel splicing mutation.PMID 17266182Read ↗

Determination of optimal conditions for analysis of p53 status in leukemic cells using functional analysis of separated alleles in yeast.Semantic proximity Read ↗

Analysis of p53 status in human cell lines using a functional assay in yeast: detection of new non-sense p53 mutation in codon 124.Semantic proximity Read ↗

Improving the detection of p53 mutations in breast cancer by use of the FASAY, a functional assay.Semantic proximity Read ↗

Yeast functional assay of the p53 gene status in human cell lines maintained in our laboratory.Semantic proximity Read ↗

[Functional screening of p53 status in tumor cells using Saccharomyces cerevisiae].Semantic proximity Read ↗

Clinical evaluation of p53 mutations in urothelial carcinoma by IHC and FASAY.Semantic proximity Read ↗

Yeast functional assay of the p53 gene status in 11 cell lines and 26 surgical specimens of human hepatocellular carcinoma.Semantic proximity Read ↗

Assessment of p53 functional activity in tumor cells and histologically normal mucosa from patients with head and neck squamous cell carcinoma.Semantic proximity Read ↗

Screening patients for heterozygous p53 mutations using a functional assay in yeast.Semantic proximity Read ↗

A comprehensive study of TP53 mutations in chronic lymphocytic leukemia: Analysis of 1287 diagnostic and 1148 follow-up CLL samples.Semantic proximity Read ↗

Acetaldehyde-induced mutational pattern in the tumour suppressor gene TP53 analysed by use of a functional assay, the FASAY (functional analysis of separated alleles in yeast).Semantic proximity Read ↗

Correlations of breast carcinoma biomarkers and p53 tested by FASAY and immunohistochemistry.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.