Article
Functional overlap between conserved and diverged KH domains in Saccharomyces cerevisiae SCP160.
Nucleic acids research - 1 Jan 2007
Brykailo Melissa A, Corbett Anita H, Fridovich-Keil Judith L
Abstract excerpt
The K homology (KH) domain is a remarkably versatile and highly conserved RNA-binding motif. Classical KH domains include a characteristic pattern of hydrophobic residues, a Gly-X-X-Gly (GXXG) segment, and a variable loop. KH domains typically occur in clusters, with some retaining their GXXG sequence (conserved), while others do not (diverged). As a first step towards addressing whether GXXG is essential for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
