Article
Determination of the genetic status of cleavage-stage human embryos by microsatellite marker analysis following multiple displacement amplification.
Prenatal diagnosis - 1 Mar 2007
Renwick Pamela J, Lewis Cathryn M, Abbs Stephen, Ogilvie Caroline Mackie
Abstract excerpt
OBJECTIVES: To analyse genotype information from cleavage-stage human embryos and assess the chromosomal status and feasibility of performing aneuploidy screening by microsatellite analysis. METHODS: DNA from 49 blastomeres from eight cleavage-stage human embryos was amplified using multiple displacement amplification, then tested for panels of 64 polymorphic microsatellite markers on seven different chromosomes,...
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