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Article

The oncogenic potential of a prostate cancer-derived androgen receptor mutant.

The Prostate - 1 May 2007

Shi Xu-Bao, Xue Lingru, Tepper Clifford G, Gandour-Edwards Regina, Ghosh Paramita, Kung Hsing-Jien, DeVere White Ralph W

Abstract excerpt

BACKGROUND: The role of androgen receptor (AR) mutations in the initiation of prostate cancer (CaP) remains unclear. The purpose of this study was to assess the influence of an AR mutation on prostate tumorigenesis and to determine the resulting molecular alterations. METHODS: Wild-type AR (AR(WT)) or the CaP-derived K580R AR (AR(K580R)) mutant was stably transfected into SV40-immortalized human prostate...

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PMID: 17262801
DOI: 10.1002/pros.20544

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ALPP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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