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Article

P2 promoter variants of the hepatocyte nuclear factor 4alpha gene are associated with type 2 diabetes in Mexican Americans.

Diabetes - 1 Feb 2007

Lehman Donna M, Richardson Dawn K, Jenkinson Chris P, Hunt Kelly J, Dyer Thomas D, Leach Robin J, Arya Rector, Abboud Hanna E, Blangero John, Duggirala Ravindranath, Stern Michael P

Abstract excerpt

Common and rare variants of the hepatocyte nuclear factor 4alpha (HNF4A) gene have been associated with type 2 diabetes and related traits in several populations suggesting the involvement of this transcription factor in diabetes pathogenesis. Single nucleotide polymorphisms (SNPs) within a large haplotype block surrounding the alternate P2 promoter, located approximately 45 kb upstream from the coding region,...

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Identifiers

PMID: 17259399
DOI: 10.2337/db06-0881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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